Unlike PRP (Platelet-Rich Plasma), PRF needs no additives or anticoagulants, and is spun at a lower speed that preserves more healing components and releases them gradually.
PRF Injections for TMJ
PRF injections use your body’s own healing power to repair the jaw joint and restore function — for patients across Raleigh, Cary and Durham.
What Are PRF Injections?
Platelet-Rich Fibrin (PRF) injections use the patient’s own blood-derived growth factors to reduce inflammation and promote healing inside the temporomandibular joint. A small blood sample is drawn, spun in a centrifuge, and the separated fibrin layer injected into the joint, where it releases cytokines and regenerative proteins slowly over time. That gradual release is what makes PRF injections for TMJ suited to joint degeneration and chronic inflammation.
Unlike corticosteroid injections, PRF regenerates tissue without synthetic agents. Dr. Charles Ferzli uses it inside a personalized plan for TMJ disorder. Unlike trigger point therapy, which is anesthetic and treats muscle, PRF is regenerative and treats the joint.

When To Seek PRF Injections

Persistent Jaw Pain
Chronic discomfort that hasn’t improved with other conservative treatments.

Joint Clicking or Popping
Sounds in the TMJ that signal underlying instability or damage.

Inflammation & Swelling
Ongoing joint tenderness or swelling affecting daily function.

Limited Jaw Movement
Difficulty opening or closing the mouth comfortably.
Our Non-Surgical PRF Approach
Joint degeneration, arthritis, injury and unresolved TMJ dysfunction damage the joint. Medication and generic appliances quiet symptoms without repairing cartilage, so pain returns. PRF stimulates your body’s own healing response instead, concentrating growth factors and stem cells at the injury site.
Natural Healing
Uses your own healing factors to repair and strengthen joint tissues.
Reduced Inflammation
Calms the swelling behind chronic pain.
Joint Protection
Promotes healthier cartilage and joint stability.
Non-Surgical Solution
Minimally invasive, little downtime, and pairs with laser therapy.

Why Choose Us?
PRF Injections is one of the specialized services we provide at the TMJ & Sleep Therapy Centre of Raleigh-Durham. Our focus is on identifying the root causes behind your symptoms and delivering safe, non-surgical solutions that support long-term health and comfort.
Start with a Simple TMJ and Sleep Screening
Do You Have TMJ?
Take our quick 2-minute assessment to find out if your symptoms may be related to TMJ disorder.
Take TMJ QuizSleep Apnea Risk?
Discover if your snoring, fatigue, or restless sleep could indicate sleep apnea with this brief screening.
Take Sleep QuizHeal Naturally with PRF Injections
You don’t have to rely on medications or invasive surgery to manage TMJ pain. At the TMJ & Sleep Therapy Centre of Raleigh-Durham, PRF injections provide a safe, natural way to restore joint health and reduce discomfort. Schedule your consultation today and take the first step toward healing.
(919) 323-4242 Message UsPRF Injection Questions
A small blood sample is drawn, processed and reinjected into the targeted area. Most patients report only mild discomfort, and recovery is usually quick.
Many patients notice less pain and better jaw mobility within the first few weeks; healing continues over several months as tissue regenerates.
Because PRF comes from your own blood, there is no risk of rejection or allergic reaction. Patients with certain blood disorders may not be candidates; your provider reviews your health history.